The increasing incidence of antibiotic resistance among bacterial pathogens necessitates medicinal plants as an alternate therapy in restricting the resistant infectious organisms. In this primitive study, the antibiotic resistance of organisms isolated from urinary tract infected patients was evaluated using the National Committee for Clinical Laboratory Standards (NCCLS) method and Multiple Antibiotic Resistance (MAR) index values, and the MAR values was also calculated for plant extracts. The 10 common medicinal plants collected from Kolli hills, Namakkal, south India were extracted using the chloroform, methanol, acetone, ethanol and saponification procedure. The efficacy of the extracts on the uropathogens was tested by agar disc diffusion method in order to analyse the inhibitory activity of plant extract on the organisms. Azadiracta indica A. Juss., Tinospora cordifolia (Wild.) and Euphorbia hirta Linn. exhibited high inhibitory activity against most of the 11 tested organisms followed by Cassia javanica Linn. and Phyllanthus niruri Linn. The maximum zone size of 46.3 mm was exhibited by methanol extract of P. niruri Linn. against Pseudomonas aeruginosa. Asparagus racemosus Willd. and Eupatorium triplinerve Vahl had the least activity against resistant pathogens. Saponified lipids of most of the plants exhibited maximum antibacterial activity. Among the tested organisms, P. aeruginosa and Staphylococcus epidermidis were the most susceptible and Serratia marcescens, Enterobacter cloaceae, Citrobacter koseri, and Citrobacter freundii were the least inhibited by most of the extracts of medicinal plants. It is concluded that revised antibiotic policies and more importantly the development of herbal medicine as an alternative may be incorporated in urological practice.
Antibacterial activity of selected medicinal plants against multiple antibiotic resistant uropathogens: a study from Kolli Hills, Tamil Nadu, India
A. Narayanan Related information
1 PG and Research Department of Microbiology, K.S. Rangasamy College of Arts and Science, KSR Kalvi Nagar, Thokkavadi Post, Tiruchengode 637 215, Tamil Nadu, India
, S. Raja Related information2 Department of Microbiology, Bharathidasan University College, Perambalur, Tiruchirapalli, Tamil Nadu, India
, K. Ponmurugan Related information1 PG and Research Department of Microbiology, K.S. Rangasamy College of Arts and Science, KSR Kalvi Nagar, Thokkavadi Post, Tiruchengode 637 215, Tamil Nadu, India
, S. Kandekar Related information3 KSR Institute of Dental Science & Research, KSR Kalvi Nagar, Thokkavadi Post, Tiruchengode 637 215, Tamil Nadu, India
, K. Natarajaseenivasan Related information4 Department of Microbiology, Bharathidasan University, Tiruchirapalli 620 024, Tamil Nadu, India
, A. Maripandi Related information5 Dept of Microbiology, Government Arts College, Dharmapuri 636 705, Tamil Nadu, India
, Q. Mandeel Related information6 Department of Biology, University of Bahrain, P.O. Box 32038, Sakhir Campus, Bahrain
Beneficial Microbes: 2
(3)- Pages: 235 - 243
Published Online: October 10, 2011
Abstract
2022 Journal Impact Factor
5.4
source: Journal Impact Factor 2023™ from Clarivate™
Institutional Offers
For institutional orders, please contact [email protected].
-
A.A. Hibberd, C.C. Yde, M.L. Ziegler, A.H. Honoré, M.T. Saarinen, S. Lahtinen, B. Stahl, H.M. Jensen and L.K. Stenman
-
E.E. Blaak, E.E. Canfora, S. Theis, G. Frost, A.K. Groen, G. Mithieux, A. Nauta, K. Scott, B. Stahl, J. van Harsselaar, R. van Tol, E.E. Vaughan and K. Verbeke
-
K. Venema, J. Verhoeven, C. Beckman and D. Keller
-
E. Arvidsson Nordström, C. Teixeira, C. Montelius, B. Jeppsson and N. Larsson
-
J.E. Haarhuis, A. Kardinaal and G.A.M. Kortman
-
E.E. Blaak, E.E. Canfora, S. Theis, G. Frost, A.K. Groen, G. Mithieux, A. Nauta, K. Scott, B. Stahl, J. van Harsselaar, R. van Tol, E.E. Vaughan and K. Verbeke
-
K. Lippert, L. Kedenko, L. Antonielli, I. Kedenko, C. Gemeier, M. Leitner, A. Kautzky-Willer, B. Paulweber and E. Hackl
-
K. Tsilingiri and M. Rescigno
-
M. Ozen and E.C. Dinleyici
-
Y. Kobayashi, T. Kuhara, M. Oki and J.-Z. Xiao