Aas, J.A., Griffen, A.L., Dardis, S.R., Lee, A.M., Olsen, I., Dewhirst, F.E., Leys, E.J. and Paster, B.J., 2008. Bacteria of dental caries in primary and permanent teeth in children and young adults. Journal of Clinical Microbiology 46: 1407-1417. Crossref, Google Scholar
	Adegbola, R.A., DeAntonio, R., Hill, P.C., Roca, A., Usuf, E., Hoet, B. and Greenwood, B.M., 2014. Carriage of Streptococcus pneumoniae and other respiratory bacterial pathogens in low and lower-middle income countries: a systematic review and meta-analysis. PLoS ONE 9: e103293. Crossref, Google Scholar
	Al-Ghutaimel, H., Riba, H., Al-Kahtani, S. and Al-Duhaimi, S., 2014. Common periodontal diseases of children and adolescents. International Journal of Dentistry 2014: 850674. Google Scholar
	Alcaraz, L.D., Belda-Ferre, P., Cabrera-Rubio, R., Romero, H., Simon-Soro, A., Pignatelli, M. and Mira, A., 2012. Identifying a healthy oral microbiome through metagenomics. Clinical Microbiology and Infection 18, Suppl. 4: 54-57. Crossref, Google Scholar
	Allen, E.K., Pitkaranta, A., Maki, M., Hendley, J.O., Laakso, S., Sale, M.M. and Winther, B., 2013. Bacteria in the nose of young adults during wellness and rhinovirus colds: detection by culture and microarray methods in 100 nasal lavage specimens. International Forum of Allergy and Rhinology 3: 731-739. Crossref, Google Scholar
	Armstrong, S.K., 2015. Bacterial metabolism in the host environment: pathogen growth and nutrient assimilation in the mammalian upper respiratory tract. Microbiology Spectrum 3(3): MBP-0007-2014. Google Scholar
	Avila, M., Ojcius, D.M. and Yilmaz, O., 2009. The oral microbiota: living with a permanent guest. DNA and Cell Biology 28: 405-411. Crossref, Google Scholar
	Bahrani-Mougeot, F.K., Paster, B.J., Coleman, S., Ashar, J., Barbuto, S. and Lockhart, P.B., 2008. Diverse and novel oral bacterial species in blood following dental procedures. Journal of Clinical Microbiology 46: 2129-2132. Crossref, Google Scholar
	Bassis, C.M., Erb-Downward, J.R., Dickson, R.P., Freeman, C.M., Schmidt, T.M., Young, V.B., Beck, J.M., Curtis, J.L. and Huffnagle, G.B., 2015. Analysis of the upper respiratory tract microbiotas as the source of the lung and gastric microbiotas in healthy individuals. MBio 6: e00037. Google Scholar
	Biesbroek, G., Bosch, A.A., Wang, X., Keijser, B.J., Veenhoven, R.H., Sanders, E.A. and Bogaert, D., 2014a. The impact of breastfeeding on nasopharyngeal microbial communities in infants. American Journal of Respiratory and Critical Care Medicine 190: 298-308. Google Scholar
	Biesbroek, G., Tsivtsivadze, E., Sanders, E.A., Montijn, R., Veenhoven, R.H., Keijser, B.J. and Bogaert, D., 2014b. Early respiratory microbiota composition determines bacterial succession patterns and respiratory health in children. American Journal of Respiratory and Critical Care Medicine 190: 1283-1292. Crossref, Google Scholar
	Biesbroek, G., Wang, X., Keijser, B.J., Eijkemans, R.M., Trzcinski, K., Rots, N.Y., Veenhoven, R.H., Sanders, E.A. and Bogaert, D., 2014c. Seven-valent pneumococcal conjugate vaccine and nasopharyngeal microbiota in healthy children. Emerging Infectious Diseases 20: 201-210. Crossref, Google Scholar
	Bogaert, D., De Groot, R. and Hermans, P.W., 2004a. Streptococcus pneumoniae colonisation: the key to pneumococcal disease. Lancet Infectious Diseases 4: 144-154. Crossref, Google Scholar
	Bogaert, D., Keijser, B., Huse, S., Rossen, J., Veenhoven, R., Van Gils, E., Bruin, J., Montijn, R., Bonten, M. and Sanders, E., 2011. Variability and diversity of nasopharyngeal microbiota in children: a metagenomic analysis. PLoS ONE 6: e17035. Crossref, Google Scholar
	Bogaert, D., Van Belkum, A., Sluijter, M., Luijendijk, A., De Groot, R., Rumke, H.C., Verbrugh, H.A. and Hermans, P.W., 2004b. Colonisation by Streptococcus pneumoniae and Staphylococcus aureus in healthy children. The Lancet 363: 1871-1872. Crossref, Google Scholar
	Bosch, A.A., Biesbroek, G., Trzcinski, K., Sanders, E.A. and Bogaert, D., 2013. Viral and bacterial interactions in the upper respiratory tract. PLoS Pathogens 9: e1003057. Crossref, Google Scholar
	Brogden, K.A. and Guthmiller, J.M., 2002. Polymicrobial diseases. ASM Press, Washington, DC, USA. Google Scholar
	Brook, I., 2016. Microbiology of chronic rhinosinusitis. European Journal of Clinical Microbiology and Infectious Diseases 35: 1059-1068. Crossref, Google Scholar
	Cagetti, M.G., Mastroberardino, S., Milia, E., Cocco, F., Lingstrom, P. and Campus, G., 2013. The use of probiotic strains in caries prevention: a systematic review. Nutrients 5: 2530-2550. Crossref, Google Scholar
	Campisi, G., Panzarella, V., Matranga, D., Calvino, F., Pizzo, G., Lo Muzio, L. and Porter, S., 2008. Risk factors of oral candidosis: a twofold approach of study by fuzzy logic and traditional statistic. Archives of Oral Biology 53: 388-397. Crossref, Google Scholar
	Canducci, F., Debiaggi, M., Sampaolo, M., Marinozzi, M.C., Berre, S., Terulla, C., Gargantini, G., Cambieri, P., Romero, E. and Clementi, M., 2008. Two-year prospective study of single infections and co-infections by respiratory syncytial virus and viruses identified recently in infants with acute respiratory disease. Journal of Medical Virology 80: 716-723. Crossref, Google Scholar
	Cerca, N., Martins, S., Sillankorva, S., Jefferson, K.K., Pier, G.B., Oliveira, R. and Azeredo, J., 2005. Effects of growth in the presence of subinhibitory concentrations of dicloxacillin on Staphylococcus epidermidis and Staphylococcus haemolyticus biofilms. Applied and Environmental Microbiology 71: 8677-8682. Crossref, Google Scholar
	Chao, Y., Marks, L.R., Pettigrew, M.M. and Hakansson, A.P., 2014. Streptococcus pneumoniae biofilm formation and dispersion during colonization and disease. Frontiers in Cellular and Infection Microbiology 4: 194. Google Scholar
	Charlson, E.S., Bittinger, K., Haas, A.R., Fitzgerald, A.S., Frank, I., Yadav, A., Bushman, F.D. and Collman, R.G., 2011. Topographical continuity of bacterial populations in the healthy human respiratory tract. American Journal of Respiratory and Critical Care Medicine 184: 957-963. Crossref, Google Scholar
	Chen, H. and Jiang, W., 2014. Application of high-throughput sequencing in understanding human oral microbiome related with health and disease. Frontiers in Microbiology 5: 508. Google Scholar
	Chonmaitree, T., Revai, K., Grady, J.J., Clos, A., Patel, J.A., Nair, S., Fan, J. and Henrickson, K.J., 2008. Viral upper respiratory tract infection and otitis media complication in young children. Clinical Infectious Diseases 46: 815-823. Crossref, Google Scholar
	Clerehugh, V., 2008. Periodontal diseases in children and adolescents. British Dental Journal 204: 469-471. Crossref, Google Scholar
	Çolak, H., Dulgergil, C.T., Dalli, M. and Hamidi, M.M., 2013. Early childhood caries update: a review of causes, diagnoses, and treatments. Journal of Natural Science, Biology, and Medicine 4: 29-38. Crossref, Google Scholar
	Colombo, A.P., Boches, S.K., Cotton, S.L., Goodson, J.M., Kent, R., Haffajee, A.D., Socransky, S.S., Hasturk, H., Van Dyke, T.E., Dewhirst, F. and Paster, B.J., 2009. Comparisons of subgingival microbial profiles of refractory periodontitis, severe periodontitis, and periodontal health using the human oral microbe identification microarray. Journal of Periodontology 80: 1421-1432. Crossref, Google Scholar
	Corby, P.M., Lyons-Weiler, J., Bretz, W.A., Hart, T.C., Aas, J.A., Boumenna, T., Goss, J., Corby, A.L., Junior, H.M., Weyant, R.J. and Paster, B.J., 2005. Microbial risk indicators of early childhood caries. Journal of Clinical Microbiology 43: 5753-5759. Crossref, Google Scholar
	Crielaard, W., Zaura, E., Schuller, A.A., Huse, S.M., Montijn, R.C. and Keijser, B.J., 2011. Exploring the oral microbiota of children at various developmental stages of their dentition in the relation to their oral health. BMC Medical Genomics 4: 22. Crossref, Google Scholar
	Curilovic, Z., Mazor, Z. and Berchtold, H., 1977. Gingivitis in Zurich schoolchildren. A reexamination after 20 years. Schweizeriche Monatsschrift für Zahnheilkunde 87: 801-808. Google Scholar
	De Martino, M. and Ballotti, S., 2007. The child with recurrent respiratory infections: normal or not? Pediatric Allergy and Immunology 18, Suppl. 18: 13-18. Crossref, Google Scholar
	De Steenhuijsen Piters, W.A., Sanders, E.A. and Bogaert, D., 2015. The role of the local microbial ecosystem in respiratory health and disease. Philosophical Transactions of the Royal Society of London. Series B, Biological Science 370: 20140294. Google Scholar
	Di Pierro, F., Colombo, M., Zanvit, A., Risso, P. and Rottoli, A.S., 2014. Use of Streptococcus salivarius K12 in the prevention of streptococcal and viral pharyngotonsillitis in children. Journal of Drug, Healthcare and Patient Safety 6: 15-20. Google Scholar
	Dickson, R.P., Erb-Downward, J.R. and Huffnagle, G.B., 2013. The role of the bacterial microbiome in lung disease. Expert Review of Respiratory Medicine 7: 245-257. Crossref, Google Scholar
	Donlan, R.M. and Costerton, J.W., 2002. Biofilms: survival mechanisms of clinically relevant microorganisms. Clinical Microbiology Reviews 15: 167-193. Crossref, Google Scholar
	Douglass, J.M., 2000. Response to Tinanoff and Palmer: dietary determinants of dental caries and dietary recommendations for preschool children. Journal of Public Health Dentistry 60: 207-209. Crossref, Google Scholar
	Duell, B.L., Su, Y.C. and Riesbeck, K., 2016. Host-pathogen interactions of nontypeable Haemophilus influenzae: from commensal to pathogen. FEBS Letters 590: 3840-3853. Crossref, Google Scholar
	Falagas, M.E., Roussos, N. and Vardakas, K.Z., 2010. Relative frequency of albicans and the various non-albicans Candida spp among candidemia isolates from inpatients in various parts of the world: a systematic review. International Journal of Infectious Diseases 14: e954-966. Crossref, Google Scholar
	Filoche, S.K., Soma, K. and Sissons, C.H., 2005. Antimicrobial effects of essential oils in combination with chlorhexidine digluconate. Oral Microbiology Immunology 20: 221-225. Crossref, Google Scholar
	Fine, D.H., 1988. Mouthrinses as adjuncts for plaque and gingivitis management. A status report for the American Journal of Dentistry. American Journal of Dentistry 1: 259-263. Google Scholar
	Garcia-Rodriguez, J.A. and Fresnadillo Martinez, M.J., 2002. Dynamics of nasopharyngeal colonization by potential respiratory pathogens. Journal of Antimicrobial Chemotherapy 50, Suppl. S2: 59-73. Crossref, Google Scholar
	Gjermo, P., Rosing, C.K., Susin, C. and Oppermann, R., 2002. Periodontal diseases in Central and South America. Periodontology 2000, 29: 70-78. Google Scholar
	Grigalauskiene, R., Slabsinskiene, E. and Vasiliauskiene, I., 2015. Biological approach of dental caries management. Stomatologija 17: 107-112. Google Scholar
	Gross, E.L., Beall, C.J., Kutsch, S.R., Firestone, N.D., Leys, E.J. and Griffen, A.L., 2012. Beyond Streptococcus mutans: dental caries onset linked to multiple species by 16S rRNA community analysis. PLoS ONE 7: e47722. Crossref, Google Scholar
	Hajishengallis, E., Parsaei, Y., Klein, M.I. and Koo, H., 2015. Advances in the microbial etiology and pathogenesis of early childhood caries. Molecular Oral Microbiology 32: 24-34. Crossref, Google Scholar
	Han, Y.W., Shi, W., Huang, G.T., Kinder Haake, S., Park, N.H., Kuramitsu, H. and Genco, R.J., 2000. Interactions between periodontal bacteria and human oral epithelial cells: Fusobacterium nucleatum adheres to and invades epithelial cells. Infection and Immunity 68: 3140-3146. Crossref, Google Scholar
	Hanage, W.P., Finkelstein, J.A., Huang, S.S., Pelton, S.I., Stevenson, A.E., Kleinman, K., Hinrichsen, V.L. and Fraser, C., 2010. Evidence that pneumococcal serotype replacement in Massachusetts following conjugate vaccination is now complete. Epidemics 2: 80-84. Crossref, Google Scholar
	Hao, Q., Dong, B.R. and Wu, T., 2015. Probiotics for preventing acute upper respiratory tract infections. Cochrane Database of Systematic Reviews: CD006895. Google Scholar
	Harriott, M.M. and Noverr, M.C., 2009. Candida albicans and Staphylococcus aureus form polymicrobial biofilms: effects on antimicrobial resistance. Antimicrobial Agents and Chemotherapy 53: 3914-3922. Crossref, Google Scholar
	Highfield, J., 2009. Diagnosis and classification of periodontal disease. Australian Dental Journal 54, Suppl. 1: S11-26. Crossref, Google Scholar
	Hilty, M., Qi, W., Brugger, S.D., Frei, L., Agyeman, P., Frey, P.M., Aebi, S. and Muhlemann, K., 2012. Nasopharyngeal microbiota in infants with acute otitis media. Journal of Infectious Diseases 205: 1048-1055. Crossref, Google Scholar
	Høiby, N., Ciofu, O., Johansen, H.K., Song, Z.J., Moser, C., Jensen, P.O., Molin, S., Givskov, M., Tolker-Nielsen, T. and Bjarnsholt, T., 2011. The clinical impact of bacterial biofilms. International Journal of Oral Science 3: 55-65. Crossref, Google Scholar
	Hong, C.K., Park, D.C., Kim, S.W., Cha, C.I., Cha, S.H. and Yeo, S.G., 2008. Effect of paranasal sinusitis on the development of otitis media with effusion: influence of Eustachian tube function and adenoid immunity. International Journal of Pediatric Otorhinolaryngology 72: 1609-1618. Crossref, Google Scholar
	Hope, C.K. and Wilson, M., 2003. Effects of dynamic fluid activity from an electric toothbrush on in vitro oral biofilms. Journal of Clinical Periodontology 30: 624-629. Crossref, Google Scholar
	Hugoson, A., Koch, G. and Rylander, H., 1981. Prevalence and distribution of gingivitis-periodontitis in children and adolescents. Epidemiological data as a base for risk group selection. Swedish Dental Journal 5: 91-103. Google Scholar
	Huse, S.M., Ye, Y., Zhou, Y. and Fodor, A.A., 2012. A core human microbiome as viewed through 16S rRNA sequence clusters. PLoS ONE 7: e34242. Crossref, Google Scholar
	Jabra-Rizk, M.A., Torres, S.R., Rambob, I., Meiller, T.F., Grossman, L.K. and Minah, G., 2007. Prevalence of oral Candida species ina North American pediatric population. Journal of Clinical Pediatric Dentistry 31: 260-263. Crossref, Google Scholar
	Jakobsson, H.E., Jernberg, C., Andersson, A.F., Sjolund-Karlsson, M., Jansson, J.K. and Engstrand, L., 2010. Short-term antibiotic treatment has differing long-term impacts on the human throat and gut microbiome. PLoS ONE 5: e9836. Crossref, Google Scholar
	Jenkinson, H.F. and Lamont, R.J., 2005. Oral microbial communities in sickness and in health. Trends in Microbiology 13: 589-595. Crossref, Google Scholar
	Kadir, T., Uygun, B. and Akyuz, S., 2005. Prevalence of Candida species in Turkish children: relationship between dietary intake and carriage. Archives of Oral Biology 50: 33-37. Crossref, Google Scholar
	Kanasi, E., Dewhirst, F.E., Chalmers, N.I., Kent Jr., R., Moore, A., Hughes, C.V., Pradhan, N., Loo, C.Y. and Tanner, A.C., 2010. Clonal analysis of the microbiota of severe early childhood caries. Caries Research 44: 485-497. Crossref, Google Scholar
	Kenealy, T. and Arroll, B., 2013. Antibiotics for the common cold and acute purulent rhinitis. Cochrane Database of Systematic Reviews: CD000247. Google Scholar
	Ketabi, M., Tazhibi, M. and Mohebrasool, S., 2006. The prevalance and risk factors of gingivitis among the children referred to Isfahan Islamic Azad University (Khorasgan branch) dental school, in Iran. Available at: http://tinyurl.com/zs35vvr. Google Scholar
	King, S., Glanville, J., Sanders, M.E., Fitzgerald, A. and Varley, D., 2014. Effectiveness of probiotics on the duration of illness in healthy children and adults who develop common acute respiratory infectious conditions: a systematic review and meta-analysis. British Journal of Nutrition 112: 41-54. Crossref, Google Scholar
	Kolenbrander, P.E., Andersen, R.N. and Moore, L.V., 1989. Coaggregation of Fusobacterium nucleatum, Selenomonas flueggei, Selenomonas infelix, Selenomonas noxia, and Selenomonas sputigena with strains from 11 genera of oral bacteria. Infection and Immunity 57: 3194-3203. Google Scholar
	Koopman, J.E., Van der Kaaij, N.C., Buijs, M.J., Elyassi, Y., Van der Veen, M.H., Crielaard, W., Ten Cate, J.M. and Zaura, E., 2015. The effect of fixed orthodontic appliances and fluoride mouthwash on the oral microbiome of adolescents – a randomized controlled clinical trial. PLoS ONE 10: e0137318. Google Scholar
	Kostakioti, M., Hadjifrangiskou, M. and Hultgren, S.J., 2013. Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era. Cold Spring Harbor Perspectives in Medicine 3: a010306. Crossref, Google Scholar
	Kranz, S., Smiciklas-Wright, H. and Francis, L.A., 2006. Diet quality, added sugar, and dietary fiber intakes in American preschoolers. Pediatric Dentistry 28: 164-171. Krcmery, V. and Barnes, A.J., 2002. Non-albicans Candida spp. causing fungaemia: pathogenicity and antifungal resistance. Journal of Hospital Infection 50: 243-260. Google Scholar
	Krom, B.P., Kidwai, S. and Ten Cate, J.M., 2014. Candida and other fungal species: forgotten players of healthy oral microbiota. Journal of Dental Research 93: 445-451. Crossref, Google Scholar
	Kuramitsu, H.K., He, X., Lux, R., Anderson, M.H. and Shi, W., 2007. Interspecies interactions within oral microbial communities. Microbiology and Molecular Biology Reviews 71: 653-670. Crossref, Google Scholar
	Kusel, M.M., De Klerk, N.H., Holt, P.G., Kebadze, T., Johnston, S.L. and Sly, P.D., 2006. Role of respiratory viruses in acute upper and lower respiratory tract illness in the first year of life: a birth cohort study. Pediatric Infectious Disease Journal 25: 680-686. Crossref, Google Scholar
	Laufer, A.S., Metlay, J.P., Gent, J.F., Fennie, K.P., Kong, Y. and Pettigrew, M.M., 2011. Microbial communities of the upper respiratory tract and otitis media in children. MBio 2: e00245-00210. Google Scholar
	Lee, J.T., Frank, D.N. and Ramakrishnan, V., 2016. Microbiome of the paranasal sinuses: update and literature review. American Journal of Rhinology and Allergy 30: 3-16. Crossref, Google Scholar
	Lemon, K.P., Klepac-Ceraj, V., Schiffer, H.K., Brodie, E.L., Lynch, S.V. and Kolter, R., 2010. Comparative analyses of the bacterial microbiota of the human nostril and oropharynx. MBio 1: e00129-10. Google Scholar
	Lenoir-Wijnkoop, I., Gerlier, L., Bresson, J.L., Le Pen, C. and Berdeaux, G., 2015. Public health and budget impact of probiotics on common respiratory tract infections: a modelling study. PLoS ONE 10: e0122765. Google Scholar
	Lif Holgerson, P., Ohman, C., Ronnlund, A. and Johansson, I., 2015. Maturation of oral microbiota in children with or without dental caries. PLoS ONE 10: e0128534. Google Scholar
	Lim, F.J., De Klerk, N., Blyth, C.C., Fathima, P. and Moore, H.C., 2016. Systematic review and meta-analysis of respiratory viral coinfections in children. Respirology 21: 648-655. Crossref, Google Scholar
	Lucas, V.S., Beighton, D. and Roberts, G.J., 2000. Composition of the oral streptococcal flora in healthy children. Journal of Dentistry 28: 45-50. Crossref, Google Scholar
	Majorana, A., Bardellini, E., Flocchini, P., Amadori, F., Conti, G. and Campus, G., 2010. Oral mucosal lesions in children from 0 to 12 years old: ten years’ experience. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology 110: e13-18. Google Scholar
	Malloy, A.M., Falsey, A.R. and Ruckwardt, T.J., 2013. Consequences of immature and senescent immune responses for infection with respiratory syncytial virus. Current Topics in Microbiology and Immunology 372: 211-231. Google Scholar
	Marks, L.R., Davidson, B.A., Knight, P.R. and Hakansson, A.P., 2013. Interkingdom signaling induces Streptococcus pneumoniae biofilm dispersion and transition from asymptomatic colonization to disease. MBio 4: e00438-13. Google Scholar
	Marom, T., Alvarez-Fernandez, P.E., Jennings, K., Patel, J.A., McCormick, D.P. and Chonmaitree, T., 2014. Acute bacterial sinusitis complicating viral upper respiratory tract infection in young children. Pediatric Infectious Disease Journal 33: 803-808. Crossref, Google Scholar
	Marsh, P.D., 2006. Dental plaque as a biofilm and a microbial community – Implications for health and disease. BMC Oral Health 6, Suppl. 1: S14. Crossref, Google Scholar
	Marsh, P.D., Moter, A. and Devine, D.A., 2011. Dental plaque biofilms: communities, conflict and control. Periodontology 2000, 55: 16-35. Crossref, Google Scholar
	Marshall, H.S., Richmond, P., Nissen, M., Lambert, S., Booy, R., Reynolds, G., Sebastian, S., Pride, M., Jansen, K.U., Anderson, A.S. and Scully, I.L., 2015. Group A streptococcal carriage and seroepidemiology in children up to 10 years of age in Australia. Pediatric Infectious Disease Journal 34: 831-838. Crossref, Google Scholar
	Matsson, L., Hjersing, K. and Sjodin, B., 1995. Periodontal conditions in Vietnamese immigrant children in Sweden. Swedish Dental Journal 19: 73-81. Google Scholar
	Mattos-Graner, R.O., Li, Y., Caufield, P.W., Duncan, M. and Smith, D.J., 2001. Genotypic diversity of mutans streptococci in Brazilian nursery children suggests horizontal transmission. Journal of Clinical Microbiology 39: 2313-2316. Crossref, Google Scholar
	Mizgerd, J.P., 2012. Respiratory infection and the impact of pulmonary immunity on lung health and disease. American Journal of Respiratory and Critical Care Medicine 186: 824-829. Crossref, Google Scholar
	Mortensen, R., Nissen, T.N., Blauenfeldt, T., Christensen, J.P., Andersen, P. and Dietrich, J., 2015. Adaptive immunity against Streptococcus pyogenes in adults involves increased IFN-gamma and IgG3 responses compared with children. Journal of Immunology 195: 1657-1664. Crossref, Google Scholar
	Nagalingam, N.A., Cope, E.K. and Lynch, S.V., 2013. Probiotic strategies for treatment of respiratory diseases. Trends in Microbiology 21: 485-492. Crossref, Google Scholar
	Nokso-Koivisto, J., Pitkaranta, A., Blomqvist, S., Jokinen, J., Kleemola, M., Takala, A., Kilpi, T. and Hovi, T., 2002. Viral etiology of frequently recurring respiratory tract infections in children. Clinical Infectious Diseases 35: 540-546. Crossref, Google Scholar
	Oh, T.J., Eber, R. and Wang, H.L., 2002. Periodontal diseases in the child and adolescent. Journal of Clinical Periodontology 29: 400-410. Crossref, Google Scholar
	Papaioannou, W., Gizani, S., Haffajee, A.D., Quirynen, M., Mamai-Homata, E. and Papagiannoulis, L., 2009. The microbiota on different oral surfaces in healthy children. Oral Microbiology and Immunology 24: 183-189. Crossref, Google Scholar
	Pihlstrom, B.L., Michalowicz, B.S. and Johnson, N.W., 2005. Periodontal diseases. The Lancet 366: 1809-1820. Crossref, Google Scholar
	Pinkham, J.R., Casamassimo, P.S., Fields, H.W., McTigue, D.J. and Nowak, A., 2005. Pediatric dentistry: infancy through adolescence. Elsevier Saunders, New York, NY, USA, 648 pp. Google Scholar
	Poole, A.C., Pischel, L., Ley, C., Suh, G., Goodrich, J.K., Haggerty, T.D., Ley, R.E. and Parsonnet, J., 2016. Crossover control study of the effect of personal care products containing triclosan on the microbiome. mSphere 1: 00056-15. Google Scholar
	Popova, M., Molimard, P., Courau, S., Crociani, J., Dufour, C., Le Vacon, F. and Carton, T., 2012. Beneficial effects of probiotics in upper respiratory tract infections and their mechanical actions to antagonize pathogens. Journal of Applied Microbiology 113: 1305-1318. Crossref, Google Scholar
	Ramberg, P., Sekino, S., Uzel, N.G., Socransky, S. and Lindhe, J., 2003. Bacterial colonization during de novo plaque formation. Journal of Clinical Periodontology 30: 990-995. Crossref, Google Scholar
	Reichart, P.A., Samaranayake, L.P. and Philipsen, H.P., 2000. Pathology and clinical correlates in oral candidiasis and its variants: a review. Oral Diseases 6: 85-91. Crossref, Google Scholar
	Revai, K., Dobbs, L.A., Nair, S., Patel, J.A., Grady, J.J. and Chonmaitree, T., 2007. Incidence of acute otitis media and sinusitis complicating upper respiratory tract infection: the effect of age. Pediatrics 119: e1408-1412. Crossref, Google Scholar
	Revai, K., McCormick, D.P., Patel, J., Grady, J.J., Saeed, K. and Chonmaitree, T., 2006. Effect of pneumococcal conjugate vaccine on nasopharyngeal bacterial colonization during acute otitis media. Pediatrics 117: 1823-1829. Crossref, Google Scholar
	Roberts, A.L., Connolly, K.L., Kirse, D.J., Evans, A.K., Poehling, K.A., Peters, T.R. and Reid, S.D., 2012. Detection of group A streptococcus in tonsils from pediatric patients reveals high rate of asymptomatic streptococcal carriage. BMC Pediatrics 12: 3. Google Scholar
	Roos, K., Holm, S.E., Grahn-Hakansson, E. and Lagergren, L., 1996. Recolonization with selected alpha-streptococci for prophylaxis of recurrent streptococcal pharyngotonsillitis – a randomized placebo-controlled multicentre study. Scandinavian Journal of Infectious Diseases 28: 459-462. Crossref, Google Scholar
	Roos, K., Holm, S.E., Grahn, E. and Lind, L., 1993. Alpha-streptococci as supplementary treatment of recurrent streptococcal tonsillitis: a randomized placebo-controlled study. Scandinavian Journal of Infectious Diseases 25: 31-35. Crossref, Google Scholar
	Rozkiewicz, D., Daniluk, T., Zaremba, M.L., Cylwik-Rokicka, D., Stokowska, W., Pawinska, M., Dabrowska, E., Marczuk-Kolada, G. and Waszkiel, D., 2006. Oral Candida albicans carriage in healthy preschool and school children. Advances in Medical Sciences 51, Suppl. 1: 187-190. Google Scholar
	Ruby, J.D., Cox, C.F., Akimoto, N., Meada, N. and Momoi, Y., 2010. The caries phenomenon: a timeline from witchcraft and superstition to opinions of the 1500s to today’s science. International Journal of Dentistry 2010: 432767. Google Scholar
	Scheie, A.A. and Petersen, F.C., 2004. The biofilm concept: consequences for future prophylaxis of oral diseases? Critical Reviews in Oral Biology and Medicine 15: 4-12. Crossref, Google Scholar
	Segata, N., Haake, S.K., Mannon, P., Lemon, K.P., Waldron, L., Gevers, D., Huttenhower, C. and Izard, J., 2012. Composition of the adult digestive tract bacterial microbiome based on seven mouth surfaces, tonsils, throat and stool samples. Genome Biology 13: R42. Crossref, Google Scholar
	Shaikh, N., Leonard, E. and Martin, J.M., 2010. Prevalence of streptococcal pharyngitis and streptococcal carriage in children: a meta-analysis. Pediatrics 126: e557-564. Crossref, Google Scholar
	Shaw, L., Harjunmaa, U., Doyle, R., Mulewa, S., Charlie, D., Maleta, K., Callard, R., Walker, A.S., Balloux, F., Ashorn, P. and Klein, N., 2016. Distinguishing the signals of gingivitis and periodontitis in supragingival plaque: a cross-sectional cohort study in Malawi. Applied and Environmental Microbiology 83: 6057-6067. Google Scholar
	Simon-Soro, A., Tomas, I., Cabrera-Rubio, R., Catalan, M.D., Nyvad, B. and Mira, A., 2013. Microbial geography of the oral cavity. Journal of Dental Research 92: 616-621. Crossref, Google Scholar
	Spijkerman, J., Van Gils, E.J., Veenhoven, R.H., Hak, E., Yzerman, E.P., Van der Ende, A., Wijmenga-Monsuur, A.J., Van den Dobbelsteen, G.P. and Sanders, E.A., 2011. Carriage of Streptococcus pneumoniae 3 years after start of vaccination program, the Netherlands. Emerging Infectious Diseases 17: 584-591. Crossref, Google Scholar
	Stahringer, S.S., Clemente, J.C., Corley, R.P., Hewitt, J., Knights, D., Walters, W.A., Knight, R. and Krauter, K.S., 2012. Nurture trumps nature in a longitudinal survey of salivary bacterial communities in twins from early adolescence to early adulthood. Genome Research 22: 2146-2152. Crossref, Google Scholar
	Stearns, J.C., Davidson, C.J., McKeon, S., Whelan, F.J., Fontes, M.E., Schryvers, A.B., Bowdish, D.M., Kellner, J.D. and Surette, M.G., 2015. Culture and molecular-based profiles show shifts in bacterial communities of the upper respiratory tract that occur with age. ISME Journal 9: 1246-1259. Crossref, Google Scholar
	Sudbery, P., Gow, N. and Berman, J., 2004. The distinct morphogenic states of Candida albicans. Trends in Microbiology 12: 317-324. Crossref, Google Scholar
	Szajewska, H., 2016. What are the indications for using probiotics in children? Archives of Disease in Childhood 101: 398-403. Crossref, Google Scholar
	Tanzer, J.M., Livingston, J. and Thompson, A.M., 2001. The microbiology of primary dental caries in humans. Journal of Dental Education 65: 1028-1037. Google Scholar
	Tatakis, D.N. and Kumar, P.S., 2005. Etiology and pathogenesis of periodontal diseases. Dental Clinics of North America 49: 491-516. Crossref, Google Scholar
	Teo, S.M., Mok, D., Pham, K., Kusel, M., Serralha, M., Troy, N., Holt, B.J., Hales, B.J., Walker, M.L., Hollams, E., Bochkov, Y.A., Grindle, K., Johnston, S.L., Gern, J.E., Sly, P.D., Holt, P.G., Holt, K.E. and Inouye, M., 2015. The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development. Cell Host and Microbe 17: 704-715. Crossref, Google Scholar
	Thompson, D.S., Carlisle, P.L. and Kadosh, D., 2011. Coevolution of morphology and virulence in Candida species. Eukaryotic Cell 10: 1173-1182. Crossref, Google Scholar
	Thompson 3rd, G.R., Patel, P.K., Kirkpatrick, W.R., Westbrook, S.D., Berg, D., Erlandsen, J., Redding, S.W. and Patterson, T.F., 2010. Oropharyngeal candidiasis in the era of antiretroviral therapy. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 109: 488-495. Crossref, Google Scholar
	Van den Bergh, M.R., Biesbroek, G., Rossen, J.W., De Steenhuijsen Piters, W.A., Bosch, A.A., Van Gils, E.J., Wang, X., Boonacker, C.W., Veenhoven, R.H., Bruin, J.P., Bogaert, D. and Sanders, E.A., 2012. Associations between pathogens in the upper respiratory tract of young children: interplay between viruses and bacteria. PLoS ONE 7: e47711. Crossref, Google Scholar
	Van Wyk, C. and Steenkamp, V., 2011. Host factors affecting oral candidiasis. Southern African Journal of Epidemiology and Infection 26: 18-21. Crossref, Google Scholar
	Venekamp, R.P., Sanders, S.L., Glasziou, P.P., Del Mar, C.B. and Rovers, M.M., 2015. Antibiotics for acute otitis media in children. Cochrane Database of Systematic Reviews: CD000219. Google Scholar
	Vissers, M., De Groot, R. and Ferwerda, G., 2014. Severe viral respiratory infections: are bugs bugging? Mucosal Immunology 7: 227-238. Crossref, Google Scholar
	Wang, J., Qi, J., Zhao, H., He, S., Zhang, Y., Wei, S. and Zhao, F., 2013. Metagenomic sequencing reveals microbiota and its functional potential associated with periodontal disease. Scientific Reports 3: 1843. Crossref, Google Scholar
	Ximénez-Fyvie, L.A., Haffajee, A.D. and Socransky, S.S., 2000. Comparison of the microbiota of supra- and subgingival plaque in health and periodontitis. Journal of Clinical Periodontology 27: 648-657. Crossref, Google Scholar
	Zaura, E., Keijser, B.J., Huse, S.M. and Crielaard, W., 2009. Defining the healthy ‘core microbiome’ of oral microbial communities. BMC Microbiology 9: 259. Crossref, Google Scholar